Scream 6 Trailer Debuts: Jenna Ortega is joined by Hayden Panettiere and Courteney Cox

Scream 6 Trailer Debuts: Jenna Ortega is joined by Hayden Panettiere and Courteney Cox

The trailer for Scream VI made its debut on Thursday morning.

Ghostface now seeks revenge in busy New York City as he attempts to track down Woodsboro survivors, played by Jenna Ortega and Melissa Barrera.

Scream VI returns Hayden Panettiere as Kirby Reed, a Scream 4 survivor, and Courteney Cox as Gale Weathers, an investigative reporter.

Creepy: The trailer for Scream 6 made its debut on Thursday morning. Ghostface now seeks revenge in busy New York City

She is back!  Hayden Panettiere stars in the trailer after taking a break from Hollywood

She is back! Hayden Panettiere stars in the trailer after taking a break from Hollywood

Sidney Prescott (Neve Campbell) is not part of Scream VI.

New cast members for Scream 6 include Samara Weaving, Liana Liberato, Dermot Mulroney, Jack Champion, Henry Czerny, Tony Revolori, Josh Segarra and Devyn Nekoda.

The sisters have a personal history with one of the first Ghostfaces, Billy Loomis (played by Skeet Ulrich).

They narrowly survive the onslaught of the new Ghostface Killers, which pushes them to leave Woodsboro behind.

She is also there: Courteney Cox can be seen as investigative reporter Gale Weathers

She is also there: Courteney Cox can be seen as investigative reporter Gale Weathers

New Face: Ghostface is now seeking revenge in busy New York City as he tries to track down Woodsboro survivors, played by Jenna Ortega (pictured) and Melissa Barrera

New Face: Ghostface is now seeking revenge in busy New York City as he tries to track down Woodsboro survivors, played by Jenna Ortega (pictured) and Melissa Barrera

In an earlier clip, the stars can be seen on a train nervously glancing at the people around them, some of whom are wearing Halloween costumes.

Ghostface seems to be a popular costume choice, as several revelers can be seen in the character’s iconic hood and mask.

However, one of them is showing clear signs that he’s someone other than just a party-goer dressed up for a night on the town.

As the lights flicker on the subway, the foursome notice a Ghostface moving closer and closer to them.

Fright: The action has shifted from a fictional California town to New York City, opening the survivors up to new forms of terror - including one played by Wednesday star Ortega

Fright: The action has shifted from a fictional California town to New York City, opening the survivors up to new forms of terror – including one played by Wednesday star Ortega

Haunted: Mindy (Jasmine Savoy Brown), Sam (Melissa Barrera, pictured)), Tara (Jenna) and Chad (Mason Gooding), all survivors from the previous Scream film, are being pursued on the subway

Haunted: Mindy (Jasmine Savoy Brown), Sam (Melissa Barrera, pictured)), Tara (Jenna) and Chad (Mason Gooding), all survivors from the previous Scream film, are being pursued on the subway

Festive: The four sit on the train and nervously look at the people around them, some of whom are wearing Halloween costumes

Festive: The four sit on the train and nervously look at the people around them, some of whom are wearing Halloween costumes

Everywhere you look, Ghostface seems to be a popular costume choice, as several revelers can be seen in the character's iconic hood and mask

Everywhere you look, Ghostface seems to be a popular costume choice, as several revelers can be seen in the character’s iconic hood and mask

1674144086 118 Scream 6 Trailer Debuts Jenna Ortega is joined by Hayden

Uh oh: One of them, however, is showing clear signs that he’s someone other than just a party-goer dressed up for a night on the town

Mindy avoids his gaze, but the fear on her face is unmistakable – especially when an electrical problem plunges the train into darkness.

In no time the lights come back on – but Mindy’s troubles have only just begun when Ghostface’s hand covers her mouth and smothers her cry for help.

As the teaser’s plot unfolds, the subtitles reveal the new film’s chilling tagline: “In a city of millions, no one can hear you scream.”

Friends legend Cox, a longtime mainstay of the Scream franchise, also returns as reporter Gale Weathers.

Horror: Mindy avoids his gaze, but the fear on her face is unmistakable - especially when an electrical problem plunges the train into darkness

Horror: Mindy avoids his gaze, but the fear on her face is unmistakable – especially when an electrical problem plunges the train into darkness

There he is: the lights come back on in no time — but Mindy's troubles have only just begun when Ghostface's hand clamps over her mouth, stifling her cry for help

There he is: the lights come back on in no time — but Mindy’s troubles have only just begun when Ghostface’s hand clamps over her mouth, stifling her cry for help

What a line: As the teaser's plot unfolds, the subtitles reveal the new film's chilling tagline:

What a line: As the teaser’s plot unfolds, the subtitles reveal the new film’s chilling tagline: “In a city of millions, no one can hear you scream”

Out of the picture: Neve has been inseparable from the franchise, which has grossed over $744 million worldwide, according to Hollywood Trade

Out of the picture: Neve has been inseparable from the franchise, which has grossed over $744 million worldwide, according to Hollywood Trade

1674144096 19 Scream 6 Trailer Debuts Jenna Ortega is joined by Hayden

Incoming: Matt Bettinelli-Olpin and Tyler Gillett, who directed the fifth Scream film, are back in the saddle directing the sixth, which ends March 10th

However, Neve revealed in an interview with Deadline earlier that year that she turned down an offer to return for Scream VI because she felt the money wasn’t enough.

“As a woman, I’ve had to work extremely hard in my career to establish my worth, especially when it comes to Scream,” she said.

“I felt like the offer I was presented didn’t match the value I brought to the franchise,” the 49-year-old actress explained.

She has been inseparable from the franchise, which has grossed over $744 million worldwide, according to Hollywood trade.

Returning: Friends legend Cox, a longtime mainstay of the Scream franchise, also returns as reporter Gale Weathers, who stars in the fifth Scream film

Returning: Friends legend Cox, a longtime mainstay of the Scream franchise, also returns as reporter Gale Weathers, who stars in the fifth Scream film

However, Neve revealed earlier this year that she turned down an offer to return for Scream VI because she felt the money wasn't enough.  She is pictured in the first Scream film in 1996

However, Neve revealed earlier this year that she turned down an offer to return for Scream VI because she felt the money wasn’t enough. She is pictured in the first Scream film in 1996

Neve later told People that “if they came to me with a number that felt right, that felt respectful, that matched my value that I brought to the franchise, I would be willing to consider later.” return for a potential screaming film.

On the other hand, Nashville actress Panettiere will return to the Scream series as the Kirby she previously played in Scream 4.

A few months ago, Hayden announced that she called the creators of Scream VI to bring her back into the franchise.

Despite not being in the fifth film, Hayden managed to pull herself back in for part six, and in July she told Good Morning America how.

“I called them myself and I was like, ‘So you guys don’t happen to want to bring Kirby back, do you?’ I did. I really wanted to be there!’ she spills.