Medicine: gene scissors keep what they promise

Medicine: gene scissors keep what they promise

On October 7, 2020 in Stockholm during the announcement of the Nobel Prize in Chemistry being awarded to Emmanuelle Charpentier and Jennifer A. Doudna for their CRISPR-Cas9 technique. Wei Xuechao/Xinhua/ABACAPRESS.COM

STORY – Ten years after its discovery, the CRISPR genome editing tool has opened up exciting perspectives.

A decade: A time that may seem long in everyday life, but is relatively short in research. However, the impact of CRISPR-Cas9 technology, a fantastic tool for manipulating the genetic code, in such a short time is impressive. And since genome editing is used in all areas of biology, all life sciences benefit from it.

Sometimes referred to as “genetic precision scissors,” the CRISPR-Cas9 tool uses a protein capable of cutting a double strand of DNA coupled to a guide RNA (to know where to go in the genetic material must be intervened). The technique was developed thanks to the collaboration between French Emmanuelle Charpentier, director of the Max Planck Research Center for Pathogenic Sciences in Berlin, and American Jennifer Doudna, professor at the University of Berkeley, California. Just eight years after their initial publication in 2012, they were awarded the Nobel Prize in Chemistry.

The applications of CRISPR are too numerous to list in detail.

Jennifer Doudna, 2020 Nobel Laureate in Chemistry, with Emmanuelle Charpentier

After ten…

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